reaching dynamics in motor cortex using 1 Cartesian spatial coordinates
نویسندگان
چکیده
3 Hirokazu Tanaka and Terrence J. Sejnowski 4 5 1 Howard Hughes Medical Institute, Computational Neurobiology Laboratory, The Salk Institute for 6 Biological Studies, La Jolla, CA 92037 7 2 School of Information Science, Japan Advanced Institute of Science and Technology, Nomi, Ishikawa 8 9231211, Japan 9 3 Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093 10 Text page: 58 11 Figures: 9 12 Reference: 95 13 Abstract: 149 words 14 Introduction: 1,343 words 15 Main text: 12,708 words (including Figure legends and Reference) 16 One-Sentence Summary: A computational model for how the motor cortex can transform intended 17 movements in external space into appropriate muscle signals in body-centered space explains a wide 18 range of otherwise inexplicable observations of motor cortex neuronal activities. 19 Running Title: Motor cortex spatial representation hypothesis 20 Corresponding author: Hirokazu Tanaka, e-mail: [email protected] 21
منابع مشابه
Computing reaching dynamics in motor cortex with Cartesian spatial coordinates.
How neurons in the primary motor cortex control arm movements is not yet understood. Here we show that the equations of motion governing reaching simplify when expressed in spatial coordinates. In this fixed reference frame, joint torques are the sums of vector cross products between the spatial positions of limb segments and their spatial accelerations and velocities. The consequences that fol...
متن کاملKinematic coordinates in which motor cortical cells encode movement direction.
During goal-directed reaching in primates, a sensorimotor transformation generates a dynamical pattern of muscle activation. Within the context of this sensorimotor transformation, a fundamental question concerns the coordinate systems in which individual cells in the primary motor cortex (MI) encode movement direction. This article develops a mathematical framework that computes, as a function...
متن کاملMotor adaptation and generalization of reaching movements using motor primitives based on spatial coordinates.
The brain processes sensory and motor information in a wide range of coordinate systems, ranging from retinal coordinates in vision to body-centered coordinates in areas that control musculature. Here we focus on the coordinate system used in the motor cortex to guide actions and examine physiological and psychophysical evidence for an allocentric reference frame based on spatial coordinates. W...
متن کاملThe Sensorimotor System Can Sculpt Behaviorally Relevant Representations for Motor Learning
The coordinate system in which humans learn novel motor skills is controversial. The representation of sensorimotor skills has been extensively studied by examining generalization after learning perturbations specifically designed to be ambiguous as to their coordinate system. Recent studies have found that learning is not represented in any simple coordinate system and can potentially be accou...
متن کاملLaterality of movement-related activity reflects transformation of coordinates in ventral premotor cortex and primary motor cortex of monkeys.
The ventral premotor cortex (PMv) and the primary motor cortex (MI) of monkeys participate in various sensorimotor integrations, such as the transformation of coordinates from visual to motor space, because the areas contain movement-related neuronal activity reflecting either visual or motor space. In addition to relationship to visual and motor space, laterality of the activity could indicate...
متن کامل